Coatings for Biostable Chronic Neural Prostheses

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$100,060.00
Award Year:
2004
Program:
SBIR
Phase:
Phase I
Contract:
1R43NS047952-01
Award Id:
71800
Agency Tracking Number:
NS047952
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
GVD CORPORATION, 19 BLACKSTONE ST, STE 1, CAMBRIDGE, MA, 02139
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
HILTON PRYCELEWIS
(617) 661-0060
HILTON@GVDCORP.COM
Business Contact:
(617) 661-0060
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I grant will support the development and testing of a fluorosilicone co-polymer coating prepared using GVD's patented nanotechnology coating process, as an insulating coating for neural prostheses. The project will focus on two specific parts of the neuroprosthetic device: lead wires and probes. In addition to electrical resistivity, these coatings will be biocompatible, stable in biological environment, ultra-thin, have good adhesion, flexibility, durability and Iow-k dielectric. Beginning with cochlear implants nearly 30 years ago and, more recently, the introduction of brain pacemakers and cortical visual implants, neural prostheses are positioned to become an increasingly common treatment of a number of neurological disorders, bringing hope to tens of millions of patients worldwide who suffer from neurological disorders such as Parkinson's disease, deep depression, and epilepsy, and don't respond to existing treatments. Coatings and surface treatments are an integral part of neuroprosthetic devices and key to their performance. Current coatings -- i.e., parylene, silicone, conventional PTFE -- are inadequate for the needs of future neuroprosthetic devices, in particular with respect to material stability, integrity and thinness. The specific aims of this project are to develop several grades fluorosilicone co-polymer coating, create samples on various wires used in neuroprosthetic devices and test for mechanical, electrical properties, and biocompatibility and stability under biological environments, and to compare with competing coating materials. Long term the objective is threefold: (1) to commercialize these coatings for neural prostheses via licensing and equipment sales to device manufacturers or coating services, (2) to expand these coatings to other medical devices, and (3) to create additional coatings using GVD's proprietary nanotechnology process.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government