Vitrified Immobilized Proteins and Ligands

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 2R44RR016833-02
Agency Tracking Number: RR016833
Amount: $732,688.00
Phase: Phase II
Program: SBIR
Awards Year: 2003
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
H AND N INSTRUMENTS, INC., 219 N WESTMOOR AVE, NEWARK, OH, 43055
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 GARY NISHIOKA
 (740) 344-4351
 GNISHIOK@ALLTEL.NET
Business Contact
 CHARLES HOLLOWAY
Phone: (740) 344-4351
Email: HNI@INFINET.COM
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): The overall objective of this research is to develop a new process and laboratory instrument capable of synthesizing microspots of vitrified immobilized proteins and ligands. Immobilized proteins and ligands stored in a vitrified (glassy) sugar matrix would be well preserved at room and even elevated temperatures. The ability to create such microspots could generate significant improvements in performance, cost, convenience, and storage requirements for applications requiring immobilized proteins and ligands. Examples of applications that could be improved include immunoassays, syntheses using immobilized enzymes, purifications involving affinity chromatography, and sensors using immobilized antibodies, enzymes, and ligands.

* Information listed above is at the time of submission. *

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