On Demand Electrospray Microarray Printer

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43RR021260-01
Agency Tracking Number: RR021260
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2005
Solicitation Year: 2005
Solicitation Topic Code: N/A
Solicitation Number: PHS2005-2
Small Business Information
H And N Instruments, Inc., 219 N Westmoor Ave, Newark, OH, 43055
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: Y
Principal Investigator
 GARY NISHIOKA
 (740) 344-4351
 hni@infinet.com
Business Contact
 CHARLES HOLLOWAY
Phone: (740) 344-4351
Email: HNI@INFINET.COM
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): Microarrays are finding increasing use by researchers in a variety of fields. While DNA microarrays have found the largest application in research, there is increasing interest in microarrays consisting of antibodies and other proteins. The overall objective of this research is to develop a commercial laboratory instrument for printing microarrays, based on electrospray technology. The proposed instrument will fulfill two needs. First, it will allow researchers to print high-density microarrays of a variety of compounds, with spot sizes on the order of few micrometers. It would be capable of the parallel printing of a large number of compounds, and could be easily reloaded with a different set of solutions. The proposed printer would match the ease of use and convenience of the contact microarrayers currently available to researchers, but be capable of printing arrays of higher density. Second, the proposed printer will also be capable of combinatorial printing of a large number of different monomers, for in situ synthesis of oligomers and polymers. This is a capability not presently available in commercial instrumentation.

* Information listed above is at the time of submission. *

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