Hawaii Biotech, Inc.

TRANSITION STATE ANALOG HAPTENS WILL BE PREPARED FOR THE ELICITATION OF ANTIBODIES WHICH CAN CATALYZE THE CONVERSION OF PALYTOXIN PRODRUGS TO PALYTOXIN.

WE WILL CONSTRUCT HYBRID POLIO/DENGUE VIRUS GENOMES IN ORDER TO DEVELOP A VACCINE FOR DENGUE VIRUS. IN THE CHIMERIC GENOMES, ONE OF TWO DENGUE VIRUS ENVELOPE GENE FRAGMENTS WILL REPLACE SEGMENT OF THE ...

WE WILL ACHIEVE THE SELECTIVE DELIVERY OF CYTOTOXIC AGENTS THROUGH THE USE OF BISPECIFIC ANTIBODIES. TAXOL IS A PROMISING NEW ANTICANCER AGENT ISOLATED IN LOW YIELD FROM THE BARK OF THE PACIFIC YEW TR ...

HIGH AFFINITY ANTIGEN-ANTIBODY BINDING IS ESSENTIALLY ANHYDROUS HYDROPHOBIC ORGANIC SOLVENTS HAS BEEN DEMONSTRATED IN OUR LABORATORY. USING AN ESTRADIOL-ANTIESTRADIOL SYSTEM, A PROTOTYPE ORGANIC PHASE ...

A PALYTOXIN PRODURG DERIVATIVE WILL BE PREPARED. THIS COMPOUND WILL BE TESTED FOR ITS DIFFERENTIAL CYTOTOXICITY COMPARED TO PALYTOXIN; AND FOR ITS ABILITY TO BE ENZYMATICALLY ACTIVATED.

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THE FOUR SEROTYPES OF DENGUE VIRUSES ARE A LEADING CAUSE OF MORBIDITY THROUGHOUT THE TROPICS AND SUBTROPICS. FOR USE IN DIAGNOSTICS AND IN SUBUNIT VACCINES AGAINST DENGUE, A RELIABLE AND INEXPENSIVE S ...

TAXOL IS A PROMISING NEW ANTICANCER DRUG, ISOLATED FROM THE BARK OF THE WESTERN YEW (TAXUS BREVEFOLIA), AND IS CURRENTLYIN PHASE II CLINICAL TRIALS. DEVELOPMENT OF THIS DRUG IS IMPEDED BY A SUPPLY SHO ...