ORGANIC PHASE IMMUNOCHEMISTRY

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: N/A
Agency Tracking Number: 10624
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1989
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
99-193 Aiea Heights Dr, Aiea, HI, 96701
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Paul G Grothaus
 Principal Investigator
 (808) 487-5565
Business Contact
Phone: () -
Research Institution
N/A
Abstract
IMMUNOCHEMICAL TECHNIQUES HAVE MANY DIVERSE APPLICATIONS. HOWEVER, THEY ARE RESTRICTED TO USE ONLY IN AQUEOUS MEDIA. ECONOMICAL TECHNIQUES FOR DIRECT ORGANIC PHASE ANALYSIS AND IMMUNOAFFINITY ISOLATION WOULD SIGNIFICANTLY BROADEN THE USEFULNESS OF ANTIBODY-BASED TECHNOLOGY. THE PURPOSE OF THIS PROJECT IS TO DETERMINE THE FEASIBILITY OF EXPLOITING ANTIGEN-ANTIBODY BINDING IN THE ORGANIC PHASE. A SERIES OF SOLVENTS, ANTIBODIES, AND ANTIGENS WILL BE SELECTED TO IDENTIFY THE PARAMETERS INFLUENCING ANTIGEN-ANTIBODY BINDINGIN SOLVENT. DETECTABLE SPECIFIC BINDING WILL BE THE BASIS FOR JUSTIFYING DEVELOPMENT OF ORGANIC PHASE IMMUNOASSAYS, AFFINITY ISOLATION TECHNIQUES, AND OTHER NOVEL APPLICATIONS FOR ANTIBODIES.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government