ORGANIC PHASE IMMUNOCHEMISTRY

Award Information
Agency:
National Science Foundation
Amount:
$50,000.00
Program:
SBIR
Contract:
N/A
Solitcitation Year:
N/A
Solicitation Number:
N/A
Branch:
N/A
Award Year:
1989
Phase:
Phase I
Agency Tracking Number:
10624
Solicitation Topic Code:
N/A
Small Business Information
Hawaii Biotechnology Group Inc
99-193 Aiea Heights Dr, Aiea, HI, 96701
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
N/A
Principal Investigator
 Paul G Grothaus
 Principal Investigator
 (808) 487-5565
Business Contact
Phone: () -
Research Institution
N/A
Abstract
IMMUNOCHEMICAL TECHNIQUES HAVE MANY DIVERSE APPLICATIONS. HOWEVER, THEY ARE RESTRICTED TO USE ONLY IN AQUEOUS MEDIA. ECONOMICAL TECHNIQUES FOR DIRECT ORGANIC PHASE ANALYSIS AND IMMUNOAFFINITY ISOLATION WOULD SIGNIFICANTLY BROADEN THE USEFULNESS OF ANTIBODY-BASED TECHNOLOGY. THE PURPOSE OF THIS PROJECT IS TO DETERMINE THE FEASIBILITY OF EXPLOITING ANTIGEN-ANTIBODY BINDING IN THE ORGANIC PHASE. A SERIES OF SOLVENTS, ANTIBODIES, AND ANTIGENS WILL BE SELECTED TO IDENTIFY THE PARAMETERS INFLUENCING ANTIGEN-ANTIBODY BINDINGIN SOLVENT. DETECTABLE SPECIFIC BINDING WILL BE THE BASIS FOR JUSTIFYING DEVELOPMENT OF ORGANIC PHASE IMMUNOASSAYS, AFFINITY ISOLATION TECHNIQUES, AND OTHER NOVEL APPLICATIONS FOR ANTIBODIES.

* information listed above is at the time of submission.

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