FUNGAL EXPRESSION OF DENGUE PROTEINS FOR VACCINES

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 18930
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1992
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Hawaii Biotechnology Group Inc
99-193 Aiea Heights Drive, Aiea, HI, 96701
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 John M Ivy
 (808) 486-5333
Business Contact
Phone: () -
Research Institution
N/A
Abstract
DENGUE VIRUSES ARE A LEADING CAUSE OF MORBIDITY THROUGHOUT THE TROPICS AND SUBTROPICS. ATTEMPTS TO DEVELOP LIVE ATTENUATED DENGUE VACCINES ANALOGOUS TO THE YELLOW FEVER VACINE HAVE BEEN UNSUCCESSFUL. IN AN EFFORT TO CONTRUBITE TO THE DEVELOPMENT OF A RECOMBINANT SUBUNIT DENGUE VACCINE, WE WILL INVESTIGATE EXPRESSION OF THE DEN-3 ENVELOPE GLYCOPROTEIN IN THE FILAMENTOUS FUNGUS NEUROSPORA CRASSA.

* information listed above is at the time of submission.

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