Synthesis of a Taxol-Cehalosporin Prodrug
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Hawaii Biotechnology Group,
99-193 Aiea Heights Drive, Aiea, HI, 96701
AbstractA Taxol prodrug derivative will be prepared. This compound will be tested for its differential cytotoxicity compared to Taxol and for its ability to be enzymatically activated. The cytotoxicity of the prodrug in combination with a monoclonal-antibody enzyme conjugate in the presence of targeted and non-targeted cells will also be examined.
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