Chitosan hemostatic device for laparoscopic applications

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R41DK072559-01
Agency Tracking Number: DK072559
Amount: $231,982.00
Phase: Phase I
Program: STTR
Awards Year: 2005
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Hemcon, Inc., 10575 Sw Cascade Ave, Ste 130, Portland, OR, 97223
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 (503) 216-6826
Business Contact
Phone: (503) 245-0459
Research Institution
 3181 S.W. Sam Jackson Pk Rd
 Nonprofit college or university
DESCRIPTION (provided by applicant): Intraoperative bleeding can be a serious problem in parenchymal organ surgery and is generally difficult to manage during laparoscopic procedures. Our long-term goal is to develop a novel internal chitosan hemostatic device that can be deployed laparoscopically to control severe bleeding. External chitosan based hemostatic dressings have been applied successfully for control of aggressive hemorrhage in varying traumatic injuries. Based upon these successful studies, Phase I of this proposal includes 1) development of a novel internal chitosan hemostatic device; 2) optimization of the laparoscopic chitosan device and development of laparoscopic techniques for its delivery; and 3) evaluation of the laparoscopic hemostatic technique in partial nephrectomy. Phase II of the proposal, will expand upon the preliminary Phase I study. It will evaluate the efficacy of the internal chitosan hemostatic device in a large scale laparoscopic study. The proposed chitosan device(s) will provide safe, effective and convenient treatment to control surgical bleeding during the laparoscopic procedure and will prevent hemorrhage and urinary leakage related post-operative complications.

* Information listed above is at the time of submission. *

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