Hipple Cancer Research

Basic Information

4100 S Kettering Boulevard
Dayton, OH, 45439

Company Profile

n/a

Additional Details

Field Value
DUNS: n/a
Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N
Number of Employees: n/a


  1. Molecular Assay for Megakaryocyte Stimulating Factor

    Amount: $747,012.00

    Megakaryocyte colony-stimulating factor (Meg-CSF) is a lineage specific factor that specifically regulates the proliferation and differentiation of megakaryocytes from bone marrow. Meg-CSF is of signi ...

    SBIR Phase II 1995 Department of Health and Human Services
  2. HPV Oncogenic Marker Assay for Cervical Carcinomas

    Amount: $64,341.00

    Cervical cancer represents the second most frequent cancer in women after breast cancer. Human papi(HPVs) are implicated as a causative agent in several human cancers, especially squamous tumors of ta ...

    SBIR Phase I 1995 Department of Health and Human Services
  3. Retinoic Acids and Cytokines in Hematopoiesis

    Amount: $99,856.00

    This Phase I application is concerned with the secretion of G-CSF by bone marrow mononuclear cellsstimulation by a combination of retinoids and natural product extract from a Chinese fungus . Retinoto ...

    SBIR Phase I 1995 Department of Health and Human Services
  4. Automated Image Analysis of Megakaryocyte Progenitors

    Amount: $100,000.00

    The objective of this feasibility study is development of a sensitive instrument, based on image ancount megakaryocyte colonies (CFU-meg), the number of megakaryocytes per colony, megakaryocyte maturp ...

    SBIR Phase I 1995 Department of Health and Human Services
  5. Indoleamine 2,3-Dioxygenase and AIDS Dementia Complex

    Amount: $88,997.00

    Patients infected with human-deficiency virus (HIV)-1 resulting in the development of acquired immusyndrome (AIDS) often develop neurological disease named AIMS Dementia Complex (ADC). The underlyingA ...

    SBIR Phase I 1995 Department of Health and Human Services
  6. AMINE OXIDASE-DEPLETED CELL CULTURE MEDIA FOR STEM CELLS

    Amount: $512,000.00

    A FAMILY OF PLASMA ENZYMES NAMED AMINE OXIDASES CONTRIBUTE TO A LACK OF SURVIVAL OF HEMATOPOIETIC PROGENITOR CELLS IN VITRO BY OXIDIZING THE AMINES RELEASED INTO THE MEDIUM INTO CYTOTOXIC AND MUTAGENI ...

    SBIR Phase II 1994 Department of Health and Human Services
  7. Development of Human Megakaryocyte Progenitor Assay

    Amount: $540,000.00

    With the advent of cytokine therapy, thrombocytopenia is the major dose-limiting toxicity of anti-cancer and anti-AIDS drugs. Early screening of developmental agents for toxicity to hematopoietic, par ...

    SBIR Phase II 1994 Department of Health and Human Services
  8. MONOCLONAL AND POLYCLONAL MAGAKARYOCYTE CSF ANTIBODIES

    Amount: $500,000.00

    THE PRODUCTION OF MEGAKARYOCYTES FROM PROGENITOR CELLS IN THE MARROW CAN BE STIMULATED BY A LINEAGE-SPECIFIC FACTOR-MEGAKARYOCYTE COLONY-STIMULATING FACTOR (MEG-CSF). THE LINEAGE-SPECIFIC STIMULATION ...

    SBIR Phase II 1993 Department of Health and Human Services
  9. A DEFINED MEGAKARYOCYTE PROGENITOR (CFU-MEG) ASSAY

    Amount: $500,000.00

    ONE OF THE TOXIC EFFECTS OF ANTI-CANCER AND ANTI-HIV CHEMOTHERAPY IS THROMBOCYTOPENIA. THE COLONY FORMING UNIT-MEGAKARYOCYTE (CFU-MEG) IS A MEASURE OF THE NUMBER OF MARROW PROGENITOR CELLS CAPABLE OF ...

    SBIR Phase II 1993 Department of Health and Human Services
  10. ADAPTION OF CAPSCAN TECHNOLOGY TO HEMATOPOIETIC ASSAYS

    Amount: $500,000.00

    THE HIPPLE CANCER RESEARCH CORPORATION DEVELOPED PATENTED TECHNOLOGY (CAPSCAN TM) FOR QUANTITATING PARTICLES INSIDE MICROCAPILLARY TUBES, INCLUDING TUMOR CELL COLONIES. HIPPLE ALSO PIONEERED MICROCAPI ...

    SBIR Phase II 1993 Department of Health and Human Services

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