POLYMERIC MEMBRANE BARRIERS FOR ANIMAL ISOLATION

Award Information
Agency:
Department of Health and Human Services
Branch:
N/A
Amount:
$416,847.00
Award Year:
1990
Program:
SBIR
Phase:
Phase II
Contract:
N/A
Agency Tracking Number:
11385
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Horizon Micro-environments
2351 College Station Rd #575, Athens, GA, 30605
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
N/A
Principal Investigator
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THIS RESEARCH WILL TEST THE FEASIBILITY OF USING INEXPENSIVE POLYMERIC MEMBRANES TO SERVE AS PASSIVE CONTAMINANT BARRIERS FOR LABORATORY ANIMALS. THEORETICAL CALCULATIONS SHOW THAT THE FLUX OF ANIMAL RESPIRATORY GASES THROUGH POLYMERIC MEMBRANES CAN BE MORE THAN SUFFICIENT TO SUPPORT LIFE FOR ANIMALS IN HERMETICALLY SEALED ENVIRONMENTS. THESE MEMBRANES COULD BE USED TO PROTECT ANIMALS FROM AIRBORNE PATHOGENS WHILE PERMITTING THE RAPID PASSAGE OF ATMOSPHERIC GASES NECESSARY FOR RESPIRATION. BESIDES PROTECTING ANIMALS FROM EXTRANEOUS CONTAMINATION, THEY CAN BE USED TO PROTECT LABORATORY PERSONNEL FROM ALLERGENS AND INFECTIOUS AGENTS. MEMBRANES SUPPORTED ON POROUS SUBSTRATES SHOULD BE USEFUL FOR ANIMAL CONTAINMENT SYSTEMS IN RESEARCH, BREEDING, HOUSING, AND SHIPPING OF RESEARCH ANIMALS THROUGHOUT THE UNITED STATES. THE RESULTING TECHNOLOGY WILL PROVIDE AN ECONOMICAL MEANS TO CONTROL ENVIRONMENTAL VARIABLES ENCOUNTERED IN ANIMAL HOUSING. RESEARCH WILL FOCUS ON DEVELOPING AN OPTIMAL MEMBRANE/SUPPORT COMBINATION. MEMBRANE/SUPPORT COMBINATIONS WILL THEN BE TESTED FOR GAS EXCHANGE WITH LIVE ANIMALS AND FOR BARRIER EFFECTIVENESS IN MICROBIAL CHALLENGES.

* information listed above is at the time of submission.

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