GASTROINTESTINAL ENDOSCOPIC OPTICAL FIBER FLUORIMETRY

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1987
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
7241
Agency Tracking Number:
7241
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
7822 Rockhill, Houston, TX, 77061
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
CHARLES KERSHAW
(713) 640-1704
Business Contact:
() -
Research Institute:
n/a
Abstract
RESEARCH ON NOVEL GASTROINTESTINAL ENDOSCOPIC OPTICAL FIBER FLUORIMETRY (GEOFF) SENSORS IS PROPOSED IN ANSWER TO THE EMPHATIC NEED FOR SIGNIFICANT GAINS IN NEW AND BETTER SENSORDEVICES IN CONNECTION WITH RESEARCH, DIAGNOSTIC, AND THERAPEUTIC ENDOSCOPIC PROCEDURES. THE MERITS OF PROMISING SINGLE- OR MULTI-STRANDED AND DISPOSABLE OPTICAL FIBER FLUORIMETRY SENSORS CONFIGURED TO AUGMENT THE FIBEROPTIC ENDOSCOPES WILL BE EVALUATED IN ANSWER TO A VARIETY OF APPLICATIONS, NAMELY: (1) INNOVATION TOWARD MORE DIRECT AND DETAILED INTERPRETATION OF TISSUE FLUORESCENCE IN VIVO USING DYES SUCH AS RHODAMINE 123 (RH-123), A MITOCHONDRIAL-SPECIFIC DYE; (2) ADAPTATIONS OF DISPOSABLE GEOFF SENSORS INTEGRATED WITH ENDOSCOPIC SYSTEMS TO UPGRADE AND EXTEND THE DIAGNOSTIC ABILITY OF ENDOSCOPIC PROCEDURES, AS WELL AS PROMOTE NEW CONFIGURATIONS OF ADVANCED ENDOSCOPIC DEVICES; AND (3) IMPLEMENTATION OF A FIRST GENERATION OF "SMART" ENDOSCOPIC DEVICES ENDOWED WITH "INTELLIGENCE" FUNCTIONS SUCH AS DETECTION, RECOGNITION, STORAGE, AND MANIPULATION OF TISSUE DATA OBTAINED FROM VISUAL AND NONVISUAL SPECTRAL CUES.

* information listed above is at the time of submission.

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