Freeze-Dried Reagents for real-time PCR

Award Information
Agency: Department of Defense
Branch: Office for Chemical and Biological Defense
Contract: F33615-02-C-6035
Agency Tracking Number: C2-0085
Amount: $746,938.00
Phase: Phase II
Program: SBIR
Awards Year: 2002
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
390 Wakara Way, Salt Lake City, UT, 84108
DUNS: 556915205
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Deepika Silva
 Director, Biochemisrty
 (801) 736-6354
Business Contact
 Todd Ritter
Title: Director, Business Develo
Phone: (801) 736-6354
Research Institution
"The Idaho Technology RAPID is currently the only fieldable DNA-based system available for monitoring threat agents such as Bacillus anthracis and Yersinia pestis. It has been deployed throughout the Air Force and other branches of the military with a highlevel of operational success. Typical PCR methods used with the RAPID are tied to complex wet chemistry more suitable for the laboratory than field environments. Our Phase I effort was directed at demonstrating that these reagents can be produced in afreeze-dried, stable format, allowing sensitive PCR methods to be used in non-laboratory environments and significantly increasing the ease of use of the RAPID system. We have successfully shown the feasibility of producing reagents in a freeze-dried formwith extended stability and no loss of performance. Idaho Technology is now in a position to provide the Air Force with a complete system that includes both the chemistry and the instrumentation required for monitoring biowarfare agents in any environment.The tasks outlined in the Phase II effort will improve upon the foundations laid down in Phase I by developing methods for scale-up of the process, and implementing a quality system that will be necessary for eventual commercialization."

* Information listed above is at the time of submission. *

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