SBIR Phase I: Electronically Actuated Low Power Microfluidic Pump

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0711986
Agency Tracking Number: 0711986
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2007
Solitcitation Year: 2006
Solitcitation Topic Code: BT
Solitcitation Number: NSF 06-598
Small Business Information
Illuminaria, LLC
117 Devlen Road, Ste 1675, Groton, NY, 13073
Duns: 145383514
Hubzone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Scott Stelick
 MEng
 (607) 592-3778
 sstelick@illuminariallc.com
Business Contact
 Scott Stelick
Title: MEng
Phone: (607) 592-3778
Email: sstelick@illuminariallc.com
Research Institution
N/A
Abstract
This Small Business Innovation Research (SBIR) Phase I research project will develop a low-cost, low-power, and disposable microfluidic Electrolytic Hydraulic Pumps (EHPs). Many emerging diagnostic and clinical applications, such as point-of-care Polymerase Chain Reaction (PCR) pathogen analysis and ambulatory drug infusion, require battery-powered fluid pumping systems that are lightweight, low power, and extremely accurate. Unfortunately, current syringe and roller pumps are too heavy and power-hungry for many portable applications. This research will develop matchbox-sized EHPs that can pump volumes ranging from 0.1 ml to 5 ml. In addition, a programmable control system that integrates an ultrasonic transit-time flow measurement system will be developed. This combination will produce a prototype that can deliver up to 5ml volumes at 3microL/minute with a 0.1microL/minute accuracy. This technology would also permit development of high-accuracy ""cigarette-pack""-sized wearable drug infusion systems. Emerging point-of-care systems analyze suspected pathogens via a PCR reaction carried out on a microfluidic chip. DNA purification and PCR reactions in the system require precise fluid delivery to ensure a reliable and repeatable pathogen analysis. The EHP Pumping system would permit design of disposable cartridges containing the pump, pre-measured reagents, and connectors. Another potential market for the proposed pumping technology would be for emerging ""animal-on-a-chip"" cell culturing systems and drug toxicology studies.

* information listed above is at the time of submission.

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