Development of a Point-of-care Assay for the Detection of Rift Valley Fever Virus, a Militarily Important Pathogen of the CENTCOM and AFRICOM Area of

Award Information
Agency:
Department of Defense
Branch:
Army
Amount:
$69,918.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-09-C-0030
Agency Tracking Number:
A083-180-0114
Solicitation Year:
2008
Solicitation Topic Code:
A08-180
Solicitation Number:
2008.3
Small Business Information
InBios International
562 1st Ave S, Suite 600, Seattle, WA, 98104
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
Y
Duns:
004006628
Principal Investigator
 Syamal Raychaudhuri
 Chief Scientific Officer
 (206) 344-5821
 raychaud@inbios.com
Business Contact
 Estela Raychaudhuri
Title: President
Phone: (206) 344-5821
Email: inbios@aol.com
Research Institution
N/A
Abstract
The objective of this study is to develop a robust, field grade, screening assay for the detection of RVFV in human blood and sera. The test will utilize a lateral flow (dipstick) chromatography incorporated into a cassette. The proposed immunochromatographic assay would be a very useful screening test to assess RVFV. This would facilitate the treatment of military personnel presenting with febrile illness. It would also help in eradication programs. In this Phase I study we will develop/acquire antibody and antigen reagents for use in development of prototype RVFV detection assays. We will then construct prototype assays that will be evaluated against archived samples from infected individuals. Further development of the assay would take place in a Phase II proposal.

* information listed above is at the time of submission.

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