A Point-of-Care Assay for the Detection of Coxiella Burnetii (Q fever) Infection in Soldiers Deployed to Iraq

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$69,456.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-09-C-0065
Agency Tracking Number:
A083-178-0430
Solicitation Year:
2008
Solicitation Topic Code:
A08-178
Solicitation Number:
2008.3
Small Business Information
InBios International
562 1st Ave S, Suite 600, Seattle, WA, 98104
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
Y
Duns:
004006628
Principal Investigator:
Syamal Raychaudhuri
Chief Scientific Officer
(206) 344-5821
raychaud@inbios.com
Business Contact:
Estela Raychaudhuri
President
(206) 344-5821
inbios@aol.com
Research Institution:
n/a
Abstract
The objective of this study is to develop a robust, field deployable, and a cost effective rapid screening assay for the detection of Q fever infection caused by Coxiella burnetii using human blood and sera. The test will utilize a lateral flow based immunochromatographic system (dipstick). The proposed assay would be a very useful screening tool to assess Q fever infection in the fields, in remote areas, and in a low complexity situation. Such a test would facilitate diagnosis and a treatment for military personnel presenting febrile illness. A rapid assay would also help in Q fever eradication programs. In this Phase I study we will develop/acquire antibody and antigen reagents for use in development of prototype Q fever detection assays. We will then construct prototype assays that will be evaluated using archived samples from infected individuals. Further development of the assay would take place in a Phase II proposal.

* information listed above is at the time of submission.

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