Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1U44NS057961-01
Agency Tracking Number: NS057961
Amount: $1,614,740.00
Phase: Phase I
Program: SBIR
Awards Year: 2006
Solicitation Year: 2006
Solicitation Topic Code: N/A
Solicitation Number: PHS2006-2
Small Business Information
INNOSENSE, LLC, 2531 W 237TH ST, STE 127, TORRANCE, CA, 90505
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 (310) 530-2011
Business Contact
Phone: (310) 530-2011
Research Institution
DESCRIPTION (provided by applicant): InnoSense LLC (ISL) proposes to investigate an array of selective elements that are optically coupled to light propagation through a set of long period grating (LPG) fibers configured in a parallel architecture. The goal is to study a technique that has the potential for developing a highly sensitive (10 ppb or better) and reliable (one false reading in a million) device. This will allow the first responders to detect metabolites of chemical warfare agents (CWAs) in biological fluids such as urine, saliva or sweat. The LPGs will be coated with chemoselective carbosiloxane polymers that have been designed rationally at the Pacific Northwest National Laboratory (PNNL) for detecting CWAs specifically using a surface acoustic wave (SAW) platform. This cross-platform utilization of the chemoselective coatings will allow ISL to utilize wavelet transformations to process 3D dataset (wavelength, amplitude and time axes). The sensor response will be post-processed using neural network multivariate algorithm. Protocols have been developed to study performance parameters of the array in spiked artificial urine samples. Studies will also be made to determine the impact of temperature, and urine components (e.g., urea, urochrome and uric acid) at concentrations exceeding upper limit of the normal range in urine. This Fast-Track SBIR Grant Application proposes to study a sensor array for potential use by the first responders. The impact of this work will be detection of chemical warfare agent metabolites in biological fluids such as urine. This sensor array is also an enabling technology for monitoring health care and environmental pollutants. Dissemination of the finding from this study will add to the body of scientific knowledge, spawn subsidiary sensor systems and provide additional commercial/societal benefits.

* Information listed above is at the time of submission. *

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