SBIR TOPIC 252 -COMMERCIALLY VIABLE SYNTHESIS OF MULTIFUNCTIONAL CANCER RECEPTOR

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$135,973.00
Award Year:
2008
Program:
SBIR
Phase:
Phase I
Contract:
N43CO0800057
Award Id:
94151
Agency Tracking Number:
N43CO0800057
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
2814 WILD PLUM CT., COLUMBIA, MO, 65201
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
787875579
Principal Investigator:
ANANDHI UPENDRAN
() -
Business Contact:
() -
Research Institute:
n/a
Abstract

In this Phase I SBIR contract, Nanoparticle Biochem Inc (NBI) proposes to develop commercially viable synthetic methodology for the production of multifunctional gold Nanoparticle-bombesin conjugate. Gold Nanoparticle-bombesin (AuNP-BBN) conjugate is a pot ential clinical imaging and therapeutic agent for the detection and treatment of GRP receptors over-expressing prostate and breast cancers. Average size of AuNP-BBN nanoconjugates are 14 nm. AuNP-BBN conjugate was developed by the funds from NCI's cancer n anoscience and nanotechnology platform grant and it is licensed to Nanoparticle Biochem Inc. Currently available methodology can yield only 10 mg quantities of AuNP-BBN. Developing a commercially-viable strategy for synthesizing AuNP-BBN nanoconjugate woul d significantly help in performing preclinical cancer imaging efficacy studies in larger animal models and preclinical toxicity studies.

* information listed above is at the time of submission.

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