BtBooster as a Biopesticide Potentiator

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$346,000.00
Award Year:
2007
Program:
SBIR
Phase:
Phase II
Contract:
2007-33610-18402
Award Id:
79709
Agency Tracking Number:
2006-00060
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
425 River Rd., Athens, GA, 30602
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
MohdAbdullah
(706) 542-2255
mamir@uga.edu
Business Contact:
CliftonBaile
CEO
(706) 542-4094
cbaile@uga.edu
Research Institute:
n/a
Abstract
Insecticidal efficacy is a major insecticide market driver. In 2004, InsectiGen" announced a scientific breakthrough, BtBooster", a new technology that enhances the performance of the leading biopesticide, Bacillus thuringiensis (Bt). BtBooster" is a peptide obtained from a cadherin-like protein of Manduca sexta (tobacco hornworm) and has no known or predicted toxicity to living organisms. It has no homology to any toxins. Yet BtBooster" can synergize the potency of existing Bt toxins and has potential as an additive to current Bt biopesticides. Ongoing Phase I research has demonstrated that BtBooster" enhances commercial Bt formulations on plants and overcomes Bt resistance in a Bt-resistant strain of Plutella xylostella (diamondback moth). Proposed Phase II research has three objectives: (1) conduct field trials to determine BtBooster" efficacy with commercially important crops, insect pests, and commercial Bt formulations, (2) evaluate the economic feasibility of BtBooster" as a Bt adjuvant, and (3) develop initial data for the EPA regulatory package. This research will move BtBooster" from laboratory and greenhouse bioassays to field trials, and take a long step toward developing a commercial product. We envision that it will broaden the opportunities for Bt-based insect control by overcoming limitations in Bt biopesticides.

* information listed above is at the time of submission.

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