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Gradient Coils to Enhance MRI Research in Mental Health

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 2R42MH064970-02
Agency Tracking Number: MH064970
Amount: $750,478.00
Phase: Phase II
Program: STTR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 2004
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
INSIGHT NEUROIMAGING SYSTEMS 39 SALISBURY ST
WORCESTER, MA 01609
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 CRAIG FERRIS
 (508) 799-6464
 INSL@INFI.NET
Business Contact
 JEAN KING
Phone: (508) 799-6464
Email: INFO@INSIGHTNEUROIMAGING.COM
Research Institution
 WORCESTER POLYTECHNIC INSTITUTE
 
100 INSTITUTE ROAD
WORCESTER, MA 01609
United States

 Nonprofit College or University
Abstract

DESCRIPTION (provided by applicant):
In Phase I of this STTR it was shown that it is technically feasible to substitute a planar gradient coil design for the conventional cylindrical coil design to provide greater working space inside magnetic resonance scanners. The planar gradient coil design increases the research potential of hundreds of small-bore ultra-high field scanners to include a variety of large animals. To expand the application of this system and expedite its commercialization potential the first year of Phase II product develop will focus on: (1) the design and integration of three gradient coils into a planar configuration, (2) incorporation of this design into small animal restrainers already fitted with radiofrequency electronics, and (3) start of a commercialization plan for production, marketing and sales of this new technology. Developing a planar gradient coil design integrated into a dual coil animal restrainer for preclinical MRI will impact on two major areas of interest to the National Institute of Mental Health: (1) improving drug discovery and drug evaluation in the treatment of mental illness, and (2) noninvasive imaging of brain structure, activity and chemistry over the life span of an animal. An essential piece of any drug discovery and development program for psychiatric disorders is evaluating brain activity and behavior in multiple animal models, particularly non-human primates. The products developed in this proposal will allow researchers to perform functional imaging/drug/development studies with enhanced signal-to- noise. The final product design will provide enhanced flexibility and usability, making it possible for the lay scientist to perform imaging on a range of research animals over a wide range of magnet field strengths and bore sizes.

* Information listed above is at the time of submission. *

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