THE LONG-TERM OBJECTIVES OF THIS PROGRAM ARE TO DEVELOP AND MANUFACTURE A LOW-COST, IN SITU SWEAT DETERMINATION SYSTEM FOR CYSTIC FIBROSIS SCREENING IN CHILDREN AND INFANTS.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 4883
Amount: $49,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1986
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Integrated Ionics Inc
2235 State Route 130, Dayton, NJ, 08810
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DR IMANTS R LAUKS
 PRINCIPAL INVESTIGATOR
 (201) 329-9555
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THE LONG-TERM OBJECTIVES OF THIS PROGRAM ARE TO DEVELOP AND MANUFACTURE A LOW-COST, IN SITU SWEAT DETERMINATION SYSTEM FOR CYSTIC FIBROSIS SCREENING IN CHILDREN AND INFANTS. USING THE PROPRIETARY TECHNOLOGY OF INTEGRATED IONICS, INC.,AN ACCURATE, TEMPERATURE-CORRECTED SODIUM AND CHLORIDE DETERMINATION CAN BE PERFORMED BY PLACING A MINIATURIZED COMBINED SWEAT COLLECTION/SENSOR UNIT ONTO THE SKIN OF THE SUBJECT. THE SENSORS WILL BE MASS FABRICATED USING SEMI- CONDUCTOR-BASED ELECTROCHEMICAL SENSORS WITH INTEGRATED ELECTRONICS. THE AIM IN THIS PHASE I PROGRAM IS TO DETERMINE THE FEASIBILITY OF SUCH A SYSTEM, PREFERABLY WITH-OUT THE NEED FOR SWEAT INDUCTION. A PHASE II EFFORT WILL THEN DEVELOP THE SENSOR UNIT AND PORTABLE RECORDING UNIT TO A POINT WHERE THE SYSTEM CAN BE MANUFACTURED AND MARKETED. THE STUDY WILL USE THE GIBSON-COOK PILOCARPINE IONTOPHORESISDETERMINATION AS A REFERENCE METHOD. THE PROPOSED TEST WILLUSE 1 UL OF SWEAT IN A DETERMINATION LASTING FIVE MINUTES AND REQUIRING LESSER-SKILLED STAFF; THIS WILL MAKE IT APPROPRIATE FOR EVEN NEONATAL SCREENING.

* information listed above is at the time of submission.

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government