Imaging Modality to Identify Angiogenesis

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$779,995.00
Award Year:
2001
Program:
SBIR
Phase:
Phase II
Contract:
DAMD17-01-C-0020
Agency Tracking Number:
A002-1809
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
INTELLIGENT OPTICAL SYSTEMS, INC.
2520 W. 237th Street, Torrance, CA, 90505
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
033449757
Principal Investigator:
Allan Wang
Senior Research Scientist
(310) 530-7130
awang@intopsys.com
Business Contact:
Reuben Sandler
President and CEO
(310) 530-7130
rsandler@intopsys.com
Research Institution:
n/a
Abstract
Angiogenesis is a critical component in many physiological and pathological processes, such as in cancer metastasis, and in the healing of wounds, bone fractures, ulcers, and other angiogenesis related diseases. There is, however, no software specificallydesigned for analyzing angiogenesis. Intelligent Optical Systems, Inc. (IOS) proposes to develop innovative, user-friendly software for the automatic, reliable, rapid, sensitive, and accurate analysis of MRA images. This software will use neural networksto classify the data acquired from the imaging analysis, and thus provide a method for the identification and analysis of angiogenesis and the diagnosis of cancer. This software will be useful for the diagnosis of early cancer growth and metastatictumors, and will enhance the capability of current imaging modalities of MRA for cancer diagnosis. This software will also have the potential for use in the diagnoses of other angiogenesis related diseases. Building on the successful results of Phase I,in Phase II IOS will finish the development of a complete intelligent imaging system suitable for investigational use in radiological practice, and will initiate U.S. Food and Drug Administration (FDA)-compliant clinical trials of the system.

* information listed above is at the time of submission.

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