Continuous Immunoassay for the Accurate Detection of Low Vapor Pressure TICs

Award Information
Agency: Department of Homeland Security
Branch: N/A
Contract: NBCHC050064
Agency Tracking Number: 0412020
Amount: $749,998.00
Phase: Phase II
Program: SBIR
Awards Year: 2011
Solicitation Year: 2004
Solicitation Topic Code: H-SB04.1-001
Solicitation Number: FY04.1
Small Business Information
2520 W. 237th Street, Torrance, CA, 90505-5217
DUNS: 033449757
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Glenn Bastiaans
 Senior Scientist
 (310) 530-7130
Business Contact
 Sandy Honda
Title: Manager, R&D Office
Phone: (424) 263-6313
Research Institution
Accidental spills or intentional releases of toxic industrial compounds (TICs) are significant threats to human life. Early detection and warning of the presence and distribution of these hazardous materials in the environment is very important in the prevention of injury and loss of human life. However, the monitoring for low vapor pressure TICS (LVTICs) in the atmosphere is problematic because these materials can be present in different forms that are not easily detected by conventional instruments. As part of a successful Phase I development effort, Intelligent Optical Systems (IOS) has demonstrated the feasibility of developing a system to sample and concentrate all forms of LVTICs in the atmosphere, and to continuously assay and detect LVTICs sampled from the atmosphere using a highly sensitive immunoassay technique. The goal of the Phase II work is to formalize and refine the design of the Phase I system to produce a tested and validated prototype capable of demonstrating the detection of LVTICs under conditions reflecting realistic monitoring and detection scenarios. In Phase II, displacement immunoassay protocols will be developed for additional classes of LVTICs, and a means to simultaneously monitor multiple classes of LVTICs will be constructed. A prototype bench level instrument, including an improved innovative air sampler, will be designed and fabricated to demonstrate the monitoring of LVTICs. At the end of Phase II, IOS will be prepared to market the monitor system to potential customers and to design the manufacturing processes needed to produce LVTIC monitors for sale to military and civilian markets.

* Information listed above is at the time of submission. *

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