Continuous Immunoassay for the Accurate Detection of Low Vapor Pressure TICs

Award Information
Agency: Department of Homeland Security
Branch: N/A
Contract: NBCHC040052
Agency Tracking Number: 04110982
Amount: $99,999.00
Phase: Phase I
Program: SBIR
Awards Year: 2004
Solicitation Year: 2004
Solicitation Topic Code: H-SB04.1-001
Solicitation Number: N/A
Small Business Information
2520 W. 237th Street, Torrance, CA, 90505
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Glenn Bastiaans
 Senior Scientist
 (310) 530-7130
 sbirproposals@intopsys.com
Business Contact
 Olivia Huang
Title: Contracts Manager
Phone: (310) 530-7130
Email: ohuang@intopsys.com
Research Institution
N/A
Abstract
There is a clear and growing need to detect and monitor for highly dangerous releases of toxic industrial compounds (TICs) for the protection of the general public. Current detection and monitoring devices are not adequate to protect against unwanted releases of low vapor TICs because of the high detection sensitivity required. Intelligent Optical Systems (IOS) proposes to provide an improved new generation of point detectors to warn of the presence of low vapor pressure TICs. These point detectors will be based on an emerging IOS technology that uses continuous membrane displacement immunoassay and that has been shown to provide highly sensitive detection of organic pollutants in water. High sensitivity is achieved by using innovative methods to concentrate the target analyte and by employing highly luminescent Quantum Dot labels for detection. This technology will be extended to the detection of vapor phase low volatility TICs through the addition of an efficient air sampling system coupled with an innovative flow assay system. The advantages of this methodology will be demonstrated via the design and evaluation of a laboratory prototype point detection instrument. In Phase II, the methodology will be expanded to enable simultaneous assay of multiple chemical agents.

* Information listed above is at the time of submission. *

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