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System for Non-Invasive EMG Motor Unit Recording

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43NS052019-01
Agency Tracking Number: NS052019
Amount: $99,905.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: PHS2005-2
Solicitation Year: 2005
Award Year: 2005
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
Intragraphix, Llc 1941 E Ramona Ave
Salt Lake City, UT 84108
United States
HUBZone Owned: No
Woman Owned: Yes
Socially and Economically Disadvantaged: No
Principal Investigator
 (801) 440-0502
Business Contact
Phone: (801) 467-6209
Research Institution

DESCRIPTION (provided by applicant): The goal of this program is to create a clinical system for non-invasively recording EMG motor unit signals. This system will use Blind Source Deconvolution (BSD) signal processing techniques to collect these signals with surface electrode arrays, rather than needle electrodes that must be inserted and manipulated by highly trained clinicians. This system will improve the speed, cost, and patient comfort of common clinical evaluations that require motor unit recording (such as Carpal Tunnel and diabetic neuropathy), and potentially improve the accuracy and diagnostic sensitivity of surface nerve conduction studies. In addition, by reducing the need for EMG needle insertion and manipulation, this system will enable new remote monitoring and telehealth diagnostic capabilities for common diseases such as Carpal Tunnel Syndrome and diabetic neuropathy. In Phase I, we will verify the ability of Blind Source Deconvolution (BSD) to extract motor unit signals from surface EMG of the thenar muscles using a 256-channel, thin-film EMG electrode array and offline data analysis. In Phase II, we will develop a compact, disposable surface electrode array and a miniaturized data acquisition system with software that implements the BSD algorithms in real-time. This final clinical system will provide audio and video displays of the recordings, quantitative measures regarding the number, size and shape of extracted motor units, and distribution information for the unit conduction velocities.

* Information listed above is at the time of submission. *

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