Compact quantitative near infrared device for combat casualty care

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$70,000.00
Award Year:
2008
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-09-C-0006
Award Id:
87272
Agency Tracking Number:
A082-119-1445
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1602 Newton Drive, Champaign, IL, 61822
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
152117347
Principal Investigator:
Dennis Hueber
Director of Engineering
(217) 359-8681
dennis.hueber@iss.com
Business Contact:
Beniamino Barbieri
President
(217) 359-8681
bb@iss.com
Research Institution:
n/a
Abstract
The early recognition of severe hemorrhage is a key factor towards reducing mortality and morbidity from battlefield insults. Although near-infrared (NIR) instruments have shown promise in recognizing hemorrhage, specific confounding factors must be solved to be reliable in early hemorrhage. Our hypothesis is that these confounding factors can be eliminated by proper light-tissue interaction modeling (frequency-domain photon migration), and by increasing spectral (1000 wavelengths) and temporal (200 ms) bandwidth. The objective of this proposal is to provide a compact point-of-care NIR instrument that is capable of quantitatively detecting early hemorrhage and monitoring therapeutic interventions. Our proposal features collaboration between (1) a leading biomedical technology company (ISS, Inc., Champaign, IL) that produces state-of-the-art NIR tissue oximeters, operates production facilities and has FDA submission experience, and (2) a university research team (Beckman Laser Institute, UC Irvine), with tissue optics experts who have experience in the assessment of traumatic injury via NIR optical methods. The existing ISS oximeter will be modified to increase information content that will solve the confounding factors. At the conclusion of Phase I, we will provide a unique NIR instrument that will be available for comprehensive validation and optimization studies (Phase II) and subsequent commercial miniaturization (Phase III).

* information listed above is at the time of submission.

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