Compact quantitative near infrared device for combat casualty care

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-09-C-0006
Agency Tracking Number: A2-3833
Amount: $779,722.00
Phase: Phase II
Program: SBIR
Awards Year: 2009
Solicitation Year: 2008
Solicitation Topic Code: A08-119
Solicitation Number: 2008.2
Small Business Information
ISS, Inc.
1602 Newton Drive, Champaign, IL, -
DUNS: 152117347
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Dennis Hueber
 Director of Engineering
 (217) 359-8681
 dennis.hueber@iss.com
Business Contact
 Beniamino Barbieri
Title: President
Phone: (217) 359-8681
Email: bb@iss.com
Research Institution
N/A
Abstract
The early recognition of severe hemorrhage is a key factor towards reducing mortality and morbidity from battlefield insults. Although near-infrared (NIR) instruments have shown promise in recognizing hemorrhage, specific confounding factors must be solved to be reliable in early hemorrhage shock detection. Our hypothesis is that confounding factors can be reduced or eliminated by i) using increased spectral and temporal information, ii) using a real-time statistical algorithm to measure the hemodynamic/cardiac behavior. The objective of this proposal is to provide a compact point-of-care NIR instrument that is capable of quantitatively detecting early hemorrhage and monitoring therapeutic interventions. Our proposal features collaboration between (1) a leading biomedical technology company (ISS, Inc., Champaign, IL) that produces state-of-the-art NIR tissue oximeters, and (2) a university research teams at UC Irvine, with tissue optics experts who have experience in the assessment of traumatic injury via NIR optical methods. The existing ISS oximeter will be modified to increase information content that will solve the confounding factors. At the conclusion of Phase I, we will provide a unique NIR instrument that will be available for comprehensive clinical validation and subsequent commercialization (Phase III).

* information listed above is at the time of submission.

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