Blood Substitutes with High Capacity of Carrying Oxygen

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$99,858.00
Award Year:
1995
Program:
SBIR
Phase:
Phase I
Contract:
1 R43 HL53803-01,
Award Id:
29501
Agency Tracking Number:
29501
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
26 Howard Street, Piscataway, NJ, 08854
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Gordhan Patel
() -
Business Contact:
() -
Research Institute:
n/a
Abstract
There is a need for a blood substitute because of a lack of donors, time consuming blood type and cimmunomodulation to the recipient, viral transmission, and the limited shelf life of donated blood.modified hemoglobin, and liposome encapsulated hemoglobin are being developed as blood substitutes.capacity to carry oxygen is lower than that of red blood cells. A novel class of compounds, having acarrying oxygen, are proposed as blood substitutes. These compounds will be synthesized, purified, aanalytical techniques. The ability of the compounds to carry and release oxygen will be determined.maximum capacity to carry oxygen will be selected and the in vitro toxicity of the selected compound

* information listed above is at the time of submission.

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