Magnetophoresis as Novel Means for Transgenesis

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$70,000.00
Award Year:
2001
Program:
SBIR
Phase:
Phase I
Contract:
2001-33610-10336
Award Id:
52119
Agency Tracking Number:
2001-00076
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
3119 Beaumont Woods Place, Honolulu, HI, 96822
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
ManfredKuehnle
(808) 521-5418
Business Contact:
GordonWallace
President
(808) 988-3170
gordon@aloha.net
Research Institute:
n/a
Abstract
Genetically engineered products offer tremendous potential as foods, medicines, and industrial materials. The novel process of magnetophoresis may be able to address shortcomings of existing gene transfer technologies for further crop improvement. We propose in this Phase I project to demonstrate the technical feasibility of magnetophoresis to reproducibly deliver small magnetic particles (micromagnets) into target tissues. Research focuses on strategies of micromagnet handling and on micromagnet geometry/composition for DNA payload sequestering. Identification of the enabling strategies in Phase I is key to our Phase II goal of demonstrating efficient plant genetic engineering by magnetophoresis using mersistems, plastids and gametes.

* information listed above is at the time of submission.

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