SBIR Phase II: Enabling High Output Metabolism in Plant Cells

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0548640
Agency Tracking Number: 0418989
Amount: $499,937.00
Phase: Phase II
Program: SBIR
Awards Year: 2006
Solicitation Year: 2003
Solicitation Topic Code: BT
Solicitation Number: NSF 03-535
Small Business Information
2800 Woodlawn Drive, Honolulu, HI, 96822
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Michele Champagne
 (808) 753-2693
Business Contact
 Gordon Wallace
Title: Mr
Phone: (808) 753-2693
Research Institution
This Small Business Innovation Research (SBIR) Phase II project aims to develop and validate a novel chloroplast transformation vector for protein expression in chloroplasts. The research project will broaden scientific understanding of the parameters of chloroplast transformation by addressing stoichiometric expression of multiple transgenes for effective engineering of pathways such as carotenogenesis, feedback regulation and expression of multimeric proteins. The commercial impact of this technology will provide an enabling strategy for expression of genes of interest in chloroplasts to potentially increase the production of high value nutraceutical and pharmaceutical compounds. Application of this technology for stable, high output metabolism with regulatory compliance will reduce production cost and increase the reliability for downstream processing and eventual commercialization.

* information listed above is at the time of submission.

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