LIFESENSORS, INC.

Basic Information

271 GREAT VALLEY PKWY
MALVERN, PA, 19355-1308

http://www.lifesensors.com

Company Profile

n/a

Additional Details

Field Value
DUNS: 060013641
Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N
Number of Employees: 15


  1. Selective inhibitors of deubiquitylases

    Amount: $225,000.00

    DESCRIPTION (provided by applicant): In the last decade there has been an explosive growth in the field of ubiquitin research, with approximately 530 human genes predicted to encode enzymes involved i ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. Deciphering the poly-ubiquitin code with isopeptide selective antibodies

    Amount: $223,710.00

    DESCRIPTION (provided by applicant): Ubiquitin (Ub), a 76 amino acid protein, is implicated in protein degradation and a myriad of cell signaling pathways, including DNA damage response, protein traff ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. Development of linkage-specific ubiquitin binding elements

    Amount: $1,473,951.00

    DESCRIPTION provided by applicant Identification quantification and isolation of low abundance proteins from complex mixtures is at best a difficult task This is especially the case for protei ...

    SBIR Phase II 2014 Department of Health and Human Services National Institutes of Health
  4. A novel fluorescent assay for ubiquitin isopeptide bond cleavage

    Amount: $945,452.00

    DESCRIPTION (provided by applicant): In the last decade there has been an explosive growth in the field of ubiquitin research, with approximately 530 human genes predicted to encode enzymes involved i ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Identification and characterization of linkage-specific ubiquitin binding element

    Amount: $296,287.00

    DESCRIPTION (provided by applicant): Identification, quantification, and isolation of low abundance proteins from complex mixtures is, at best, a difficult task. This is especially the case for prote ...

    SBIR Phase I 2012 Department of Health and Human Services
  6. A novel fluorescent assay for ubiquitin isopeptide bond cleavage

    Amount: $234,971.00

    DESCRIPTION (provided by applicant): As the prominence of the ubiquitin and ubiquitin-like pathways increases the need for assays to measure the activity of the enzymes involved in these pathways grow ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. Dissecting ubiquitin pathway selectivity with Ub-isopeptide microarrays

    Amount: $278,218.00

    DESCRIPTION (provided by applicant): The network of enzymes involved in the ubiquitination (ligases) and deubiquitination (deubiquitinases or DUbs) of cellular proteins is one of the largest in the hu ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Biomarker Discovery: Ubiquitin Pathway Protein Microarrays

    Amount: $1,180,320.00

    DESCRIPTION (provided by applicant): Bioinformatics and biochemical analysis suggests that the human genome encodes ~ 100 proteins known as deubiquitinating enzymes (DUBs). DUBs constitute an importan ...

    SBIR Phase II 2009 Department of Health and Human Services
  9. Development of a Novel Method to Enhance Therapeutic Protein Production

    Amount: $283,530.00

    DESCRIPTION (provided by applicant): The first step in any protein therapeutic exercise is expression of the protein. In some cases, this step is not troublesome. For increasing numbers of designer pr ...

    SBIR Phase I 2008 Department of Health and Human Services
  10. SUMO Fusions to Enhance Expression of Membrane Proteins

    Amount: $1,180,590.00

    DESCRIPTION (provided by applicant): Rather modest success has yet been achieved in expressing and purifying membrane proteins as a prerequisite to obtain high resolution structures. Only 124 unique s ...

    SBIR Phase II 2008 Department of Health and Human Services

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