Diode-Pumped Continuous-Wave Ultraviolet Laser Sources

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1993
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
22142
Agency Tracking Number:
22142
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1161 San Antonio Road, Mountain View, CA, 94043
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
David C. Gerstenberger
(415) 962-0755
Business Contact:
() -
Research Institute:
n/a
Abstract
Highly-sensitive detection techniques are required in many aspects of biotechnology. One highly sensitive technique for detecting trace levels of proteins and other biomolecular species is capillary electrophoresis with laser-induced-fluorescence detection. Capillary electrophoresis with direct laser excitation of biochemical species using ultraviolet light is especially sensitive. The objective of Phase I is to determine the feasibility of a compact and efficient optical source in the 266nm ultraviolet spectral region by frequency-quadrupling the continuous-wave output of a diode- pumped Nd:YAG laser. The long range goal is to develop a 266nm laser source in the 10-100 mW power range for use in clinical instrumentation. The compactness and reliability of such sources should lead to the development of instrumentation useful in recombinant DNA, monoclonal antibody and biopharmaceutical research.

* information listed above is at the time of submission.

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