High Performance Wafer-Based Capillary Electrochromatography

Award Information
Agency:
National Aeronautics and Space Administration
Branch
n/a
Amount:
$599,998.00
Award Year:
2005
Program:
SBIR
Phase:
Phase II
Contract:
NNG05CA20C
Agency Tracking Number:
034366
Solicitation Year:
2003
Solicitation Topic Code:
B5.03
Solicitation Number:
n/a
Small Business Information
Los Gatos Research
67 East Evelyn Avenue, Suite 3, Mountain View, CA, 94041-1518
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
928805761
Principal Investigator:
Hong Jiao
Principal Investigator
(650) 965-7772
h.jiao@lgrinc.com
Business Contact:
Anthony O'Keefe
President
(650) 965-7772
a.okeefe@lgrinc.com
Research Institution:
n/a
Abstract
The Phase II research comprises designing, constructing, and testing a chip-based capillary electrochromatography (CEC) prototype for separation and analysis of organic and inorganic molecules including amino acids and ions. The innovation of the proposed technology stems from its ability to achieve high sample retention and selectivity and yet maintain high separation efficiency, thus filling an important gap between the current technologies of capillary electrophoresis (CE) and high performance liquid chromatography (HPLC). Such microfluidics devices will enable analyte samples to be prepared, processed, and analyzed in "lab-on-a-chip" (LOC) type instrumentation in Micro Laboratories applications. In addition, they will be engineered for integration with established LOC analysis systems. The Phase II Research will address issues related to the performance and production methods for the technology. Commercial devices based on the Phase II prototype will be constructed and subsequently refined and commercialized during Phase III.

* information listed above is at the time of submission.

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