Programmable Transdermal Drug Delivery

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43AR055837-01
Agency Tracking Number: AR055837
Amount: $99,996.00
Phase: Phase I
Program: SBIR
Awards Year: 2008
Solicitation Year: 2008
Solicitation Topic Code: N/A
Solicitation Number: PHS2007-2
Small Business Information
DUNS: 928805761
HUBZone Owned: Y
Woman Owned: Y
Socially and Economically Disadvantaged: Y
Principal Investigator
 () -
Business Contact
Phone: (650) 965-7772
Research Institution
DESCRIPTION (provided by applicant): Prostate cancer and central precocious puberty linked through improper gonadal steroid levels - are most common in either the elderly or youth populations. Similar gonadal steroid problems also connected to endometrios is. Some traditional methodologies for treating these illnesses involves daily injections of medicine, which can become painful or be forgotten, result in under-dosing. Los Gatos Research is developing an alternative method for delivering time-controlled d rug formulations that is practically pain free. Furthermore, the novel technology provides an extended, programmable release platform that helps patients avoid the need to remember to take medication (particularly important for portions of the elderly popu lation) and offers the potential to use less medicine to produce the same effect due to the ability to customize the delivery to the individual patient. The technologies developed in this proposed project enable programmable, microfluidic transdermal patch es to provide a means for delivering large molecular weight drug formulations that is controlled, painless, and direct. The specific aims of the Phase I project include fabricating the unique programmable transdermal patches, testing and validating their p erformance capabilities, and optimizing them for rapid, controlled delivery of medication to control gonadal steroid levels.

* Information listed above is at the time of submission. *

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