Novel Instrumentation for Nitric Oxide Measurements in Biological Samples

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$99,358.00
Award Year:
2008
Program:
SBIR
Phase:
Phase I
Contract:
1R43GM083491-01
Award Id:
89183
Agency Tracking Number:
GM083491
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
LOS GATOS RESEARCH, 67 E EVELYN AVE, STE 3, MOUNTAIN VIEW, CA, 94041
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
928805761
Principal Investigator:
() -
Business Contact:
() -
Research Institute:
n/a
Abstract
DESCRIPTION (provided by applicant): In this Small Business Innovative Research Phase I project, Los Gatos Research (LGR) proposes to develop and test a novel mid-infrared laser-based NO Analyzer for measurements of nitric oxide concentration in cellular m edia (biological samples) over a wide dynamic range (from picomole to micromole) and with a high sensitivity (picomole). The instrument will be based on LGR's patented Off-Axis ICOS technology. In this Phase I effort, LGR is collaborating with the Universi ty of Alabama Huntsville (UAH) to develop and deploy and test this novel portable instrument. System performance will be demonstrated first in gravimetrically prepared gas samples at LGR and subsequently in aqueous biological samples at UAH. The results wi ll be validated by direct comparison with conventional chemiluminescence analyzers (at LGR) and electrochemical probes (at UAH).

* information listed above is at the time of submission.

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