SBIR Phase I: A Lateral Field Excited Immunosensor for Pathogenic Bacteria in Drinking Water

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0539598
Agency Tracking Number: 0539598
Amount: $99,999.00
Phase: Phase I
Program: SBIR
Awards Year: 2006
Solicitation Year: 2005
Solicitation Topic Code: EL
Solicitation Number: NSF 05-557
Small Business Information
Target Technology Center, Orono, ME, 04473
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Lester French
 (207) 581-2239
Business Contact
 John Vetelino
Title: Mr
Phone: (207) 581-2264
Research Institution
This Small Business Innovation Research Phase I project will demonstrate the feasibility of a lateral field excited (LFE) acoustic wave immunosensor for the detection of the pathogenic bacteria, E. coli, in drinking water. Current methods of testing drinking water for E. coli have several major drawbacks, which include time- and labor-intensive sample collection and lengthy laboratory analyses that can take at least 24 hours. The research objectives will be to optimize the LFE electrode geometry resulting in a maximum sensing area and efficient excitation of the thickness shear mode in AT-cut quartz and to determine the LFE immunosensor sensitivity, selectivity, response time, and reproducibility for the detection of non-enteropathogenic E. coli and compare them to similar results obtained using the standard quartz crystal microbalance (QCM). The Phase I work will result in an immunosensor that is not only directly applicable for the in situ determination of drinking water quality but may also be applicable for a wide range of applications in areas such as environmental safety, homeland security, agriculture, and medicine.

* Information listed above is at the time of submission. *

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