SBIR/STTR Phase I: New GUS Substrates for Cell Regulation

Award Information
Agency:
National Science Foundation
Amount:
$99,972.00
Program:
SBIR
Contract:
N/A
Solitcitation Year:
N/A
Solicitation Number:
N/A
Branch:
N/A
Award Year:
2002
Phase:
Phase I
Agency Tracking Number:
0215231
Solicitation Topic Code:
N/A
Small Business Information
Marker Gene Technologies
1850 Millrace Drive, Eugene, OR, 97403
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
N/A
Principal Investigator
 John Naleway
 (541) 342-3760
 jnaleway@oregon.uoregon.edu
Business Contact
Phone: () -
Research Institution
N/A
Abstract
This Small Business Innovation Research (SBIR) Phase I project is to develop commercial uses for conjugates capable of exploiting cloned gene expression in transformed plant cells to control their growth and physiology. The specific goal of this project is to synthesize a series of new beta-glucuronide conjugates of plant regulatory substances and to test these conjugates for their ability to modify the growth and protein expression of specific tissues and cells expressing the beta-glucuronidase (GUS) marker gene. Conjugates will be assayed in tissue culture and in whole plants for the ability to cause localized cell death in a promoter dependent manner. Such compounds will be of general use for plant research on the control of development and gene expression and have the potential to produce agriculturally important plant species in a reversible manner, through the use of selective application of substrate and choice of reporter gene and promoter elements. The commercial application of this project is in the area of agricultural biotechnology.

* information listed above is at the time of submission.

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