MATTEK CORPORATION

Address

200 HOMER AVE
ASHLAND, MA, 01721-1717

Information

DUNS: 147365936
# of Employees: N/A

Ownership Information

Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N

Award Charts




Award Listing

  1. Validation of an In Vitro Human Airway Model for Regulatory Toxicity Testing

    Amount: $431,027.00

    Results of Phase II research indicate that formal validation of the EpiAirway in vitro human bronchial tissue model for predicting toxicity of inhaled chemicals is an attainable goal The proposed Ph ...

    SBIRPhase II2017Department of Health and Human Services National Institutes of Health
  2. An In Vitro Human Small Intestine Tissue Model for Drug Permeation Studies

    Amount: $1,156,802.00

    DESCRIPTION provided by applicant Approximately of currently marketed drugs are orally administered formulations whose clinical efficacy critically depends on the absorption from the small inte ...

    SBIRPhase II2016Department of Health and Human Services National Institutes of Health
  3. An In Vitro Human Small Intestine Tissue Model for Drug Permeation Studies

    Amount: $218,331.00

    DESCRIPTION (provided by applicant): The perioral route for drug administration remains the most convenient way of clinical therapy and is preferred by patients, however, good bioavailability is a nec ...

    SBIRPhase I2014Department of Health and Human Services
  4. Genetically modified tissue engineered in vitro human models

    Amount: $966,454.00

    DESCRIPTION (provided by applicant): The goal of the current proposal is to apply state-of-the-art gene modification technology, including lentiviral delivery systems and RNA interference (RNAi) techn ...

    SBIRPhase II2012Department of Health and Human Services
  5. Validation of Human Vaginal Tissue Assay for Endocrine Disruptors

    Amount: $993,515.00

    DESCRIPTION (provided by applicant): Environmental or occupational exposure to a broad variety of chemical agents can alter normal endocrine function. The effects of these endocrine disruptors (ED) ...

    SBIRPhase II2011Department of Health and Human Services
  6. Human Corneal Model for Ocular Irritation Assay

    Amount: $924,517.00

    DESCRIPTION (provided by applicant): Replacement of the Draize rabbit eye test for ocular irritancy testing remains an elusive goal. Many believe a corneal full thickness (CFT) model is necessary to c ...

    SBIRPhase II2011Department of Health and Human Services
  7. Validation of an In Vitro Human Airway Model

    Amount: $835,982.00

    DESCRIPTION (provided by applicant): Hazard assessment, including evaluation of acute inhalation toxicity potential, is a mandatory international regulatory requirement for chemicals utilized in inter ...

    SBIRPhase II2011Department of Health and Human Services
  8. In Vitro Human Tissue Model for Intravaginal Drug Delivery

    Amount: $267,914.00

    DESCRIPTION (provided by applicant): Due to the avoidance of first-pass hepatic metabolism and gastrointestinal irritation, intravaginal administration is an attractive option for systemic delivery of ...

    SBIRPhase I2010Department of Health and Human Services
  9. Validation of a Human In Vitro Vaginal Irritation Test

    Amount: $1,205,750.00

    DESCRIPTION (provided by applicant): During Phase 1 research, the effects of 6 model test materials on a highly differentiated vaginal- ectocervical (VEC) tissue model were studied. Effects on tissue ...

    SBIRPhase II2009Department of Health and Human Services
  10. Reconstructed Skin Micronucleus Genotoxicity Assay

    Amount: $819,104.00

    DESCRIPTION (provided by applicant): As part of a standard toxicological evaluation, all new products must be tested to insure they are not genotoxic. Animal tests are available but European legislat ...

    SBIRPhase II2009Department of Health and Human Services

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