Totally Implantable Artificial Lung

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1 R43 HL53168-01A1,
Agency Tracking Number: 29495
Amount: $741,500.00
Phase: Phase II
Program: SBIR
Awards Year: 1997
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
245 Jackson Industrial Drive,, Ann Arbor, MI, 48103
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Jean Montoya
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
A totally implantable intrapleural artificial lung (AL) is presented. The AL is designed to fully spatients who require long term (more than one month) artificial gas exchange support necessary for tThe device will also provide a bridge to lung transplantation when lung recovery is impossible. Theperfused entirely by the right ventricle while the device is placed in series or in parallel with thpulmonary artery (PA) to PA, or PA to left atrium. MC3 has prototyped several extremely low resistanartificial lungs, and in collaboration with the University of Michigan, has successfully implanted tacute sheep experiments. In these experiments the AL was capable of fully supporting adult sheep whidrop across the device was tolerable by the right ventricle. Our objective in Phase I will be to furand to fully characterize the hemodynamics and gas exchange of devices that are made from silicone mmicroporous hollow fibers. This characterization will be helpful in determining how the various desiresistance to blood flow and gas exchange. Based on these results we will improve the design to advaat long term use.

* Information listed above is at the time of submission. *

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