Simple Automatic Perfusion System for salvage after cardiac arrest

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$94,861.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
1R44HL091606-01A2
Award Id:
93916
Agency Tracking Number:
HL091606
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
MC3, INC., 3550 W LIBERTY RD, STE 3, ANN ARBOR, MI, 48103
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
806687406
Principal Investigator:
DANIEL MAZUR
(734) 995-9089
MAZUR@MC3CORP.COM
Business Contact:
OSTERHOLXER KATHRYN
() -
koster@mc3corp.com
Research Institute:
n/a
Abstract
DESCRIPTION (provided by applicant): Extracorporeal support (ECPR) improves survival in resuscitation from cardiac arrest from 5% to 30%. Extracorporeal support facilitates the salvage of donor organs after cardiac death (DCD). The Institute of Medicine re port states that innovative methods to salvage DCD organs are the highest priority in organ transplantation. However ECS is rarely used for these applications. The limiting factor is the need for a simple automatic perfusion system which is inherently safe , can be initiated by paramedical personnel, and provides full support without operator intervention. MC3 is uniquely positioned to develop such a device. The research team at the University of Michigan has demonstrated that ECPR is feasible and results in 30% healthy survival. The same team has shown that mechanical organ perfusion after death by cardiac arrest (DCD-ECS) restores liver and kidney function to transplantable status. Moreover, after transplantation these DCD-ECS organs are even more successfu l than organs from heart-beating brain dead donors. The goal of this research project is to design and produce a simple Automatic Perfusion System (APS) for extracorporeal support to facilitate ECPR and organ salvage from donors after cardiac arrest. PUBLI C HEALTH RELEVANCE The goal of this research project is to design and produce a simple Automatic Perfusion System (APS) for extracorporeal support as an adjunct to CPR in cardiac arrest, and to facilitate organ salvage from donors after cardiac arrest. ECP R can increase healthy survival in arrest from 5% to 30%. Salvaging organs from cardiac arrest donors could increase the availability of organs tenfold.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government