THE CONTINUING INCREASE IN THE APPLICATION OF CYTOGENETIC PRACTICES IN MEDICINE, INDUSTRY, AND PUBLIC HEALTH HAS PLACED CONSIDERABLE STRESS ON LABORATORY FACILITIES WHICH CAN ONLY BE RESOLVED BY AUTOMATION.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1985
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
2991
Agency Tracking Number:
2991
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
11160 Warner Avenue 303,, Fountain Valley, CA, 92708
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
JOHN H. MELNYK
PRINCIPAL INVESTIGATOR
(714) 549-9373
Business Contact:
() -
Research Institute:
n/a
Abstract
THE CONTINUING INCREASE IN THE APPLICATION OF CYTOGENETIC PRACTICES IN MEDICINE, INDUSTRY, AND PUBLIC HEALTH HAS PLACED CONSIDERABLE STRESS ON LABORATORY FACILITIES WHICH CAN ONLY BE RESOLVED BY AUTOMATION. CYTOGENETIC TESTING OF INDIVIDUALS WITH DEVELOPMENTAL DISABILITIES, INFERTILITY, SPONTANEOUS ABORTION, AND LEUKEMIA IS CONDUCTED MANUALLY USING TEST TUBES AND PASTEUR PIPETTES. SIMILAR PROCEDURES ARE USED IN SCREENING INDUSTRIAL EMPLOYEES, IN TESTING DRUGS AND CHEMICALS, AND IN EVALUATING POPULATIONS EXPOSED TO ENVIRONMENTAL HAZARDS. THERE IS AN IMMEDIATE NEED FOR AN INEXPENSIVE PROCESSOR WHICH WILL NOT ONLY PROCESS LARGE NUMBERS OF SPECIMENS BUT WILL ALSO PRODUCE SPECIMEN SLIDES WITH UNIFORMLY HIGH QUALITY. THIS PROPOSAL PROVIDES THE ESSENTIAL DETAILS FOR CONSTRUCTING AND TESTING SUCH A PROCESSOR. THE PHASE I RESEARCH AND TESTING EFFORT WILL INVOLVE OPTIMIZATION OF DESIGN CONCEPTS FOR THIS NEW SYSTEM WHICH WERE DEVELOPED OVER THE PAST TWO YEARS. THE RESEARCH PLAN WILL CONSIST OF 1.OPTIMIZATION OF MECHANISM FOR DISPENSING CELLS, 2.OPTIMIZATION OF RESUSPENSION OF CELLS, A FOLLOWUP FUNDING COMMITMENT TO ACCOMPANY PHASE II IS BEING NEGOTIATED

* information listed above is at the time of submission.

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