Noninvasive Arterial Blood Gas Standard

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43HL083670-01A2
Agency Tracking Number: HL083670
Amount: $105,732.00
Phase: Phase I
Program: SBIR
Awards Year: 2007
Solicitation Year: 2007
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
MEDICAL PHYSICS, INC.
MEDICAL PHYSICS, INC., 825 NORTH 300 WEST, STE 420, SALT LAKE CITY, UT, 84103
DUNS: 145966557
HUBZone Owned: Y
Woman Owned: Y
Socially and Economically Disadvantaged: Y
Principal Investigator
 JUSTIN CLARK
 (801) 532-0221
 medicalphysics1@hotmail.com
Business Contact
 BARBARA FREED
Phone: (801) 532-0221
Email: medicalphysics1@hotmail.com
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): Blood gases are by far the most frequently monitored chemical parameters. Arterial oxygen (PaO2) is needed to assess the efficiency of O2 exchange. Arterial carbon dioxide (PaCO2) is needed to assess efficiency of ventilation and is most useful for ventilator management. However, because arterial blood sampling is not practical in many clinical situations, there is a need for noninvasive blood gas monitoring which does not rely on laboratory measurements for references. This proposal introduces a new concept for a noninvasive arterial blood monitor which applies metabolic correction applied to transcutaneous carbon dioxide measurements. The correction is derived from cutaneous oxygen metabolism data obtained from the differences of arterial and transcutaneous oxygen measurements at the site of the cutaneous carbon dioxide sensor. The new principle incorporates automatic calibration of cutaneous measurements and a sufficiently low skin contact temperature, to eliminate the need for periodic relocation of the measuring device. The arterial oxygen measurement utilizes a new concept of pressure enhancement applied to pulse oximetry. Because arterial blood sampling is not practical in many clinical situations, there is a need for noninvasive blood gas monitoring which does not rely on laboratory measurements for references. The overall goal of the project is to develop a monitor which can provide accurate and reliable blood gas data, noninvasively, without need for additional laboratory measurements for reference.

* information listed above is at the time of submission.

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