SBIR Phase II: DNA Binding Proteins as Biosensors

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0321520
Agency Tracking Number: 0214985
Amount: $498,375.00
Phase: Phase II
Program: SBIR
Awards Year: 2004
Solitcitation Year: N/A
Solitcitation Topic Code: N/A
Solitcitation Number: N/A
Small Business Information
Mediomics, LLC
815 Wenneker Drive, Saint Louis, MO, 63124
Duns: N/A
Hubzone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Ewa Heyduk
 PI
 (314) 997-5918
 yiechang@mediomics.com
Business Contact
 Yie-Hwa Chang
Phone: (314) 577-8150
Email: changyh@slu.edu
Research Institution
N/A
Abstract
This Small Business Innovation Research (SBIR) Phase II project will complete the development of biosensors for detection of heavy metals and acyl-CoA using sequence-specific DNA binding proteins. The presence of the target molecule will be reported by the biosensor as a change in fluorescence signal that could be read using a hand-held battery-operated reader. The commercial application of this project is in the area of biosensors for markets that include basic and applied research, clinical diagnosis, environmental monitoring, drug screening, and process control in manufacturing operations.

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government