ABLATABLE MASK FOR LASER REPROFILING OF THE CORNEA

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 19238
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1992
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Mediventures Inc
15250 Mercantile Drive, Dearborn, MI, 48120
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Raymond L Henry
 (313) 336-6644
Business Contact
Phone: () -
Research Institution
N/A
Abstract
STUDIES ARE DESIGNED TO DEVELOP CORNEAL MASKS, FORMED IN SITU, WITH KNOWN CENTRAL RADII OF CURVATURE. MASK FORMATION WILL UTILIZE A NEW TECHNOLOGY, ALLOWING APPLICATION OF A VISCOUS FLUID TO SMOOTHE OVER ALL CORNEAL IRREGULARITIES BEFORE GELLING IN PLACE. MASK FIRMNESS WILL BE ACHIEVED CHEMICALLY IN THE PRESENCE OF A HARD CONTACT LENS. LENS REMOVAL WILL LEAVE AN ABLATABLE MASK OF THE SAME CURVATURE TO GUIDE AN EXCIMER LASER TO LEAVE AN EXACT REPLICA OF THE LENS CURVATURE ON THE CORNEA. RABBIT EXPERIMENTS WILL DETERMINE THE OPTIMAL MASK MATRIX FOR RAPID SETTING, GOOD ABLATION CHARACTERISTICS, AND REPRODUCIBLE CENTRAL RADII OF CURVATURE. INDUCED SCARS AND ASTIGMATIC AREAS WILL BE ABLATED AWAY WHILE REPROFILING THE CORNEAL SURFACE. THE RABBIT FEASIBILITY STUDIES WILL GUIDE PROCEDURES FOR FUTURE STUDIES IN CATS FOR CORNEAL CHANGES REQUIRED TO CORRECT MYOPIC AND HYPEROPIC CONDITIONS. CONDITION OF THE EYE WILL BE COMPARED TO POSTOPERATIVE RESULTS BY NINE-RING CORNEOSCOPIC PHOTOANALYSIS MYOPIC AND HYPEROPIC CONDITIONS, SCARS, OPACITIES, AND ASTIGMATISM CAN THEORETICALLY BENEFIT FROM LASER SURGERY. SOME 140 MILLION U.S. CITIZENS USE CORRECTIVE VISION DEVICES. TOGETHER WITH THERAPEUTIC SURGERIES, THE MARKET POTENTIAL IS LARGE.

* information listed above is at the time of submission.

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