Multi-Zone Flow Through Membrane and Reagents for Onsite Detection of Domoic Acid

Award Information
Agency: Department of Commerce
Branch: N/A
Contract: DG133R-07-CN-0170
Agency Tracking Number: 07-38
Amount: $95,000.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: 8.3.2
Solicitation Number: NOAA-2007-1
Solicitation Year: 2007
Award Year: 2007
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
4802 Glendarion Drive, Durham, NC, 27713
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Thomas Stewart
 (919) 493-0688
Business Contact
 Thomas Stewart
Title: President
Phone: (919) 493-0688
Research Institution
There is a need for a simple, affordable method for measuring domoic acid in the field. This project will develop a rapid, onsite kit for domoic acid featuring a filter membrane that produces a readable color response without need for instrumentation. The filter membrane contains three or more zones with different assay characteristics in close proximity. These zones will indicate different concentrations of domoic acid by a variation in color intensity on the membrane. A modified inkjet printer will be used for the low cost production of immunoassay membranes. Phase I will focus on: 1) Production of two or more anti-domoic acid antibodies with different detection limits. 2) Use of a modified inkjet printer to deposit controlled quantities of antibodies in precise zones on a membrane. 3) Demonstration of domoic acid detection on these membranes Phase II will incorporate the membranes into a commercially available onsite test kit.

* Information listed above is at the time of submission. *

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