Controlled intracavitary prostate cancer hyperthermia

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$733,592.00
Award Year:
1996
Program:
SBIR
Phase:
Phase II
Contract:
1 R43 GM52644-01A1,
Award Id:
29452
Agency Tracking Number:
29452
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
310-312 School Street, Acton, MA, 01720
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Kenneth Carr
() -
Business Contact:
() -
Research Institute:
n/a
Abstract
This proposal defines the development and evaluation of a dedicated microwave device for rapid, autstandardized fixation of tissue biopsies for histopathological examination. Microwave energy is useddilute aldehyde or salt solutions to produce fixation results that are equal in quality to chemicalto freezing methods. Microwave fixation is in limited use by many pathology laboratories throughoutmicrowave ovens are the primary microwave device in use in the laboratory environment but have sever(e.g., nonuniform irradiation) and safety (e.g., cannot adequately vent toxic chemicals) limitationsmicrowave fixation device is important for patient care and research because it shortens the preparaspecimen in the laboratory, improves technician safety and may improve the accuracy of diagnoses. Wa single mode microwave device that uniformly irradiates biopsy tissue and controls final irradiationoninvasively using a proven radiometer; and 2) evaluate the microscopic anatomy and staining qualitspecial stains (e.g., Masson Trichrome, PAS, silver stains) of rat tissues (e.g., liver, brain, muscthe prototype microwave device.

* information listed above is at the time of submission.

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