Advanced Bioaerosol Sampler for Continuous Surveillance

Award Information
Agency:
Department of Homeland Security
Branch
n/a
Amount:
$747,607.00
Award Year:
2005
Program:
SBIR
Phase:
Phase II
Contract:
NBCHC050058
Award Id:
69256
Agency Tracking Number:
0413003
Solicitation Year:
2004
Solicitation Topic Code:
H-SB04.1-003
Solicitation Number:
n/a
Small Business Information
415 N. Quay, Bldg A, Suite 3, Kennewick, WA, 99336-
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
016541877
Principal Investigator:
VanessaKenning
Sampler Sytems Manager
(509) 222-2017
vkenning@mesosystems.com
Business Contact:
BobbiKeen
Controller
(509) 222-2015
bkeen@mesosystems.com
Research Institute:
n/a
Abstract
Many integrated biodetection systems require an aqueous sample, with the notable exception being those based on mass spectrometry which frequently uses a dry sample (MALDI or pyrolysis). The proposed air sampling system (BioXC) to be developed is amenable to dry or nearly dry sample collection, but can deliver a final sample in an aqueous format autonomously. The automated system will filter out particles larger than 10 microns, concentrate and collect particles between 1 and 10 microns, and elute the sample to a small volume of liquid (<1 ml). Furthermore, the proposed system offers significant operating and cost advantages relative to more conventional wet-walled cyclones in use today for homeland security and military applications. Another common sampling technique in use today is dry filtering, but this approach is not amenable to fully-autonomous operation. Several subsystems will be optimized and developed to provide pre-filtration, concentration, collection, and elution. These subsystems will be integrated into an autonomous system which performs dry collection of aerosols with automated elution of the sample for analysis. This integrated system will result in a sampler that can be integrated with a broad range of advanced bio-detection technologies including mass spectrometry, microchip arrays, PCR and immunoassays.

* information listed above is at the time of submission.

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