Novel Devices for Management of Toxic Alcohol Exposure

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 2R44GM062145-02A2
Agency Tracking Number: 1R43GM062145-01
Amount: $745,598.00
Phase: Phase II
Program: SBIR
Awards Year: 2005
Solicitation Year: 2005
Solicitation Topic Code: N/A
Solicitation Number: PHS2005-2
Small Business Information
MICRONIX, INC.
Micronix, Inc., 14950 Greyhound Ct, Ste 307, Carmel, IN, 46032
DUNS: N/A
HUBZone Owned: N
Woman Owned: Y
Socially and Economically Disadvantaged: N
Principal Investigator
 HANS KLOEPFER
 (317) 844-4324
 MICRONIXINC@EARTHLINK.NET
Business Contact
 MARY GAUNT-KLOEPFER
Phone: (317) 844-4324
Email: MICRONIX@EARTHLINK.NET
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): The applicant organization proposes to develop ultra-miniaturized, minimally invasive test wand methods for quantification in whole blood specimens of methanol, formate, ethylene glycol, and glycolate, the four critical analytes in the laboratory evaluation of toxic alcohol exposure. The methods dose and transport a blood sample in the nanoliter range to an integrated polymeric detection site. The detection site embodies dried chemical reagents capable of reacting with analyte, as well as a polymeric composition capable of absorbing a defined volume of blood plasma while preventing cellular component of blood from penetrating the composition. Cells are wholly removed from the detection site by proprietary chemical and physical mechanisms, thereby obviating the need for a separate cell-filtering material and unmasking the detection site for instrumented or visual analysis. Instrumented analysis is performed by means of a hand-held transmittance monitoring meter. Test procedure and performance time are streamlined by consolidating all testing steps into one single disposable device. Primary target markets are emergency room and other critical care environments.

* information listed above is at the time of submission.

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