Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 1R43DK059219-01
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2001
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
14950 GREYHOUND CT, STE307, CARMEL, IN, 46032
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 () -
Business Contact
Phone: (317) 844-4324
Research Institution
DESCRIPTION (Adapted from the Investigator's Abstract): Liver failure is a major cause of death in the U.S. There is a great need for a liver assist device for temporary support of liver failure patients. Algenix is developing a bioartificial liver to meet this critical need. As the first generation enters clinical trials, Algenix will develop a second generation device employing hepatocyte spheroids. These self-assembled spheroids exhibit long viability and enhanced liver functions in culture. The proposed work is to conduct a study of design parameters and to initiate animal trials using a rabbit liver failure model. PROPOSED COMMERCIAL APPLICATION: This project will develop a bioartificial liver for liver failure patients.

* Information listed above is at the time of submission. *

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