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Novel, rapid and accurate blood tests for detecting hereditary cancer risk

Award Information
Agency: Department of Defense
Branch: Air Force
Contract: FA8649-22-P-1061
Agency Tracking Number: FX212-CSO1-0147
Amount: $694,922.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: AF212-CSO1
Solicitation Number: X21.2
Solicitation Year: 2021
Award Year: 2022
Award Start Date (Proposal Award Date): 2022-07-22
Award End Date (Contract End Date): 2023-10-24
Small Business Information
Corporation Trust Center 1209 Orange St
Wilmington, DE 19801-1120
United States
DUNS: 079605574
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Ishraq Alim
 (917) 327-5278
Business Contact
 Andrew Paul
Phone: (770) 656-6484
Research Institution

10% of cancers are associated with an inherited pathogenic variant that can partially be identified by cancer gene panel testing, but up to 40% of cases show variants of uncertain significance (VUS) or no pathogenic variant results. VUS or no pathogenic variant do not reassign risk and, are confusing for how to proceed with surveillance/prevention. Morgan & Mendel Genomics (MMG) has developed rapid and accurate blood tests for detecting a wide range of hereditary cancer risks (breast, ovarian, colon, endometrial & pancreatic cancers) and repair mechanism responses when DNA is damaged, based on the cutting-edge flow variant assay technology. Active-duty service personnel and veterans have an increased risk for developing breast and prostate cancers. The DAF wishes to provide more accurate clinical results to inform patients and providers of cancer risks allowing for more effective treatment plans leading to improved health outcomes. MMG’s test kits can be used as companion diagnostics to annotate VUS and potentially, a standalone test. Our main goals in this project are to leverage MMG’s low-cost blood test solution of high sensitivity (>0.98), high specificity (>0.99) and rapid results (in

* Information listed above is at the time of submission. *

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