TISSUE-EQUIVALENT MRI CARDIAC PHANTOMS

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 7156
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1987
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
747 Cutter Lane, Elk Grove Village, IL, 60007
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 JOHN A URBON PHD
 (312) 894-3171
Business Contact
Phone: () -
Research Institution
N/A
Abstract
LONG-TERM OBJECTIVES INCLUDE: (1) DEVELOPMENT OF AN INEXPENSIVE, MAGNETIC RESONANCE IMAGING (MRI) TISSUE-EQUIVALENT MATERIAL; (2) CONSTRUCTION OF MRI QUALITY ASSURANCE STANDARDS; AND (3) DEVELOPMENT OF COMPLEX TISSUE-EQUIVALENT ANTHROPOMORPHIC MRI PHANTOMS TO AID IN DETECTION OF PATHOLOGICAL CONDITIONS. THE FIRST TWO GOALS WILL BENEFIT THE HEALTH CARE INDUSTRY THROUGH THE DEVELOPMENT OF INNOVATIVE TECHNOLOGY, PRODUCING COMPLEX PERFORMANCE PHANTOMS TO AID IN THE ASSESSMENT OF NEW MRI DIAGNOSTIC INSTRUMENTATION AND PROVIDING QUALITY ASSURANCE FOR EXISTING SYSTEMS. ATTAINMENT OF THE THIRD GOAL WILL HELP IMPROVE CLINICAL DIAGNOSTIC METHODS AND LEAD TO IMPROVED, LOWER COST PATIENT CARE. GOAL ATTAINMENT IS PREDICATED UPON DEVELOPMENT OF SUITABLE MRI TISSUE-EQUIVALENT SUBSTANCES. PRELIMINARY EXPERIMENTS INDICATE THAT GEL-WATER COMPOSITES, COMPOSED OF A MODIFIED POLYSACCHARIDE USED IN RF-MICROWAVE HYPERTHERMIA PHANTOMS AND APPROPRIATE MODIFYING AGENTS, SHOW PROMISE AS MRI TISSUEEQUIVALENTS. PHASE I WILL INVOLVE SYSTEMATIC EVALUATION OF THE NUCLEAR MAGNETIC RESONANCE (NMR) PROPERTIES OF THIS MATERIAL USING A 7- TO 60-MHZ-PULSED NMR SPECTROMETER, CONSTRUCTION OF TISSUE-LIKE COMPOSITES, AND THE EVALUATION OF COMPOSITE IMAGING QUALITIES AND STABILITY WITH A 0.5 TESLA MRI DEVICE. CONCURRENTLY, NOVEL MOLDING TECHNIQUES TOPRODUCE CONTIGUOUS REGIONS OF DISSIMILAR NMR WILL BE EXAMINED.

* Information listed above is at the time of submission. *

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